Trevor Lawrence, Jacksonville at New York Jets: I know that it has been rough playing Trevor Lawrence in fantasy. Lawrence and the Jaguars get to put the Urban Meyer experience in their rearview mirror. The Jets are the best possible match-up.
Ronald Jones II, Tampa Bay at Carolina: Ronald Jones II should be the top waiver-wire addition in week 16. We are projecting Leonard Fournette to miss this week, and Jones should have the Buccaneers backfield all to himself.
Devin Singletary, Buffalo at New England: Devin Singletary has emerged from the Buffalo Bills backfield. Singletary trusted as the every-down back. Even in a tough match-up, Singletary is an RB2.
Duke Johnson Jr., Miami at New Orleans: The Miami Dolphins may not run the ball against New Orleans. I would expect them to frequently target the running back out of the backfield. Duke Johnson is in play again.
Samaje Perine, Cincinnati vs. Baltimore: Keep an eye on the Bengals’ injury report. Joe Mixon was injured last week. He returned, but you will want to see him practice early this week. If Mixon is unavailable, Samaje Perine would be the next man up.
Antonio Brown, Tampa Bay at Carolina: Antonio Brown becomes incredibly necessary for the Buccaneers’ offense. Chris Godwin is out of the season, and Mike Evans is questionable heading into the week. AB would gobble up targets, so double check your waiver wire.
Amon-Ra St. Brown, Detroit at Atlanta: Amon-Ra St. Brown has emerged as the top receiving option for the Detroit Lions. Jared Goff is targeting St. Brown relentlessly. I love Amon-Ra in this match-up against the Atlanta Falcons.
Laquon Treadwell, Jacksonville at New York Jets: I have been reluctant to include Laquon Treadwell on this list–I didn’t believe. Desperate times call for desperate measures, and Treadwell has a role in the Jaguars’ offense for the remainder of the season.
Tyler Johnson, Tampa Bay at Carolina: Tyler Johnson is a deep waiver-wire addition for all of the same reasons that we laid out for Antonio Brown.
Evan Engram, New York Giants at Philadelphia: The Eagles have been horrible against the TE position all year. I understand it is tough to trust Evan Engram, but the opportunity exists.
C.J. Uzomah, Cincinnati vs. Baltimore: The Baltimore Ravens are injury-riddled in the back half of their defense. C.J. Uzomah is capable of a blow-up week and is widely available in fantasy leagues.