Taysom Hill, New Orleans vs. Dallas: We have been waiting for Taysom to get a chance under center, and it appears that time has finally arrived.
Alexander Mattison, Minnesota at Detroit: Dalvin Cook will miss a few weeks. Alexander Mattison will step into the every-down role and perform as a borderline RB1.
Jamaal Williams, Detroit vs. Minnesota: D’Andre Swift should be considered questionable at best. Jamaal Williams will step in and receive the majority of the workload for Detroit.
Boston Scott, Philadelphia at New York Jets: Boston Scott will get the starting nod and 20+ touches if Miles Sanders misses this game. The Jets are dead-last in the league against the running back position.
Matt Breida, Buffalo vs. New England: Matt Breida has been involved in the Buffalo Bills offense more often with every passing week.
Sony Michel, Los Angeles Rams vs. Jacksonville: Darrell Henderson Jr. has an injured quad. If he were to miss Sunday’s game, Sony Michel would be in a terrific fantasy situation.
Chuba Hubbard/Ameer Abdullah, Carolina (BYE): You will have to be patient on this play due to the Panthers’ bye week. Christian McCaffrey is now on the season-ending IR. Both Chuba Hubbard and Ameer Abdullah are worth picking up.
Phillip Lindsay, Houston vs. Indianapolis: Anyone that receives double-digit touches is worth something in fantasy football. Even Phillip Lindsay.
T.Y. Hilton, Indianapolis at Houston: T.Y. Hilton destroys the Houston Texans every time they play. Buy the narrative.
Rondale Moore, Arizona at Chicago: The last time we saw Rondale Moore, he had an 11-catch day. Moore is worth a pickup to see what role he has in the Cardinals offense following the bye week.
Kendrick Bourne, New England at Buffalo: Kendrick Bourne is fresh off a two-touchdown performance. If he remains available, make sure to pick him up.
Jauan Jennings, San Francisco at Seattle: With Deebo Samuel set to miss a few weeks, Jauan Jennings will step into a role in the 49ers offense.
Foster Moreau, Las Vegas vs. Washington: With Darren Waller out for at least one week, Foster Moreau steps in for an every-down role.